Noticeable changes in your metabolism (weight, temperature and energy) may be a sign of symptom that there is an imbalance of thyroid hormones in your blood. With this test panel, key hormones (TSH, T4, T3) are measured to help determine whether your thyroid is overactive (hyperthyroidism) or underactive (hypothyroidism) and monitor if your current treatment plan is working properly to manage your thyroid disease.